By E.W. Caspari (Ed.)
This quantity in a chain on genetics, emphasizes the variety of genetic reports. Articles conceal the filamentous fungus neurospora, biogenesis of yeast ribosomes, evolutionary genetics of fish, drosophila transposable parts and the dropophila gene zeste.
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Extra info for Advances in Genetics, Vol. 19
Cho+ on the trisomic segment in VII was lost, so that thc two choA alleles on the segments attached to I L become expressed. In conclusion, it has been possible to select primary unbalanced crossovers from all diploids heterozygous for T l ( 1 ; V I I ) and Td(l;VIII),but in all cases only half of the possible types were viable enough to be recoverable. This is not unexpected, since in both translocations one break is located quite distal, the other close, to a centromere, creating translocation segments of very different lengths.
These show mainly a chromosomal type of segregation of markers, and give 1 : 2 ratios for recessive :dominant alleles, if the recessive one is present on two homologs [no specifically nondisjunction inducing agent has been identified; nitrosoguanidine (NG) produced a fair number of trisomics ; however, Na-azide successfully used by Vig (1973a) has not yet been checked]. 3. Abnormally growing types which, from single nuclei, produce a variety of haploid and multiply nondisjunctional diploid patches or sectors (but few and relatively small areas of hyperploid conidia).
Random Loss of Chromosomes. That the frequent loss of chromosomes was basically a random process was demonstrated in two ways: (i) All haploids, which constituted about one-third of all color segregants, were classified for loss of homologs for every linkage group. The resulting frequencies then were compared with that expected on the basis of random loss (Table 15). As can be seen from these results, very few cases are found where the observed frequencies differ significantly from the expected ones, and in three of these cases the known reduced viability of the corresponding mutants is likely to be the main cause (homologs Ia, Ic, and I I I b ; only for one, sbA on VIb, does the extremely low recovery remain unexplained).